Nudc Gene Summary [Rat]

Predicted to enable unfolded protein binding activity. Involved in nuclear migration and response to peptide hormone. Predicted to be located in cytosol; midbody; and mitotic spindle. Predicted to be active in cytoplasm. Orthologous to human NUDC (nuclear distribution C, dynein complex regulator). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nudc
Official Name
nuclear distribution C, dynein complex regulator [Source:RGD Symbol;Acc:3215]
Ensembl ID
ENSRNOG00000051720
Bio databases IDs NCBI: 29648 Ensembl: ENSRNOG00000051720
Aliases nuclear distribution C, dynein complex regulator
Synonyms c15, HNUDC, LOC100911422, MNUDC, NPD011, nuclear distribution C, dynein complex regulator, nudC nuclear distribution protein, SIG-92, Silg92
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nudc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CS domain
  • N-terminal conserved domain of Nudc
  • alpha-crystallin Hsps/p23-like
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • expression in
  • formation
  • formation in
  • migration
  • maturation
  • transport in
  • misalignment in
  • organization
  • misalignment

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • spindle apparatus
  • Nucleus
  • midbody
  • cytosol
  • nucleoplasm
  • mitotic spindle

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nudc gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell division
  • mitotic spindle organization
  • nuclear migration
  • protein folding
  • mitotic metaphase plate congression
  • response to peptide hormone stimulus

Cellular Component

Where in the cell the gene product is active
  • mitotic spindle
  • cytoplasm
  • spindle
  • cytosol
  • midbody
  • microtubule
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • cadherin binding
  • unfolded protein binding

Gene-Specific Assays for Results You Can Trust

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