H2az2 Gene Summary [Rat]
Predicted to enable molecular adaptor activity. Predicted to be a structural constituent of chromatin. Predicted to be involved in heterochromatin formation. Predicted to be part of nucleosome. Predicted to be active in nucleus. Orthologous to human H2AZ2 (H2A.Z variant histone 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | H2az2 |
| Official Name | H2A.Z variant histone 2 [Source:RGD Symbol;Acc:1587865] |
| Ensembl ID | ENSRNOG00000052275 |
| Bio databases IDs | |
| Aliases | H2A.Z variant histone 2 |
| Synonyms | C530002L11Rik, DKFZP564D246, H2AFV, H2AV, H2A.Z-2, H2A.Z histone variant 2, H2A.Z variant histone 2, Novel histone h2a family member, Tg(Wnt1-cre)11Rth, Wnt1-Cre, Wnt1::Cre |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat H2az2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone fold domain (HFD) superfamily
- C-terminus of histone H2A
- Histone 2A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat H2az2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- heterochromatin assembly
- chromatin organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- nucleosome
Molecular Function
What the gene product does at the molecular level
- structural constituent of chromatin
- protein heterodimerization activity
- nucleosomal DNA binding
- binding, bridging