Dhx57 Gene Summary [Rat]

Predicted to enable RNA binding activity and helicase activity. Orthologous to human DHX57 (DExH-box helicase 57). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Dhx57
Official Name
DExH-box helicase 57 [Source:RGD Symbol;Acc:1310340]
Ensembl ID
ENSRNOG00000054272
Bio databases IDs NCBI: 366532 Ensembl: ENSRNOG00000054272
Aliases DExH-box helicase 57
Synonyms AW494914, DDX57, DExH-box helicase 57
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dhx57 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • UBA domain-like superfamily
  • Helicase associated domain (HA2)
  • Oligonucleotide/oligosaccharide-binding (OB)-fold
  • CCCH-type zinc finger
  • DEAD/DEAH box helicase
  • helicase superfamily c-terminal domain
  • Zinc finger C-x8-C-x5-C-x3-H type (and similar)
  • protein binding
  • Helicase conserved C-terminal domain
  • zinc finger
  • Helicase associated domain (HA2) Add an annotation
  • RNA-binding, Nab2-type zinc finger
  • RWD, DRWD, and ELF domain family
  • N-terminal helicase domain of the DEAD-box helicase superfamily
  • RWD domain
  • zinc finger domain
  • DEAD-like helicases superfamily
  • P-loop containing Nucleoside Triphosphate Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Dhx57 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • intracellular

Molecular Function

What the gene product does at the molecular level
  • ATPase activity
  • ATP binding
  • RNA binding
  • protein binding
  • RNA helicase activity
  • metal ion binding
  • helicase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.