Dhx57 Gene Summary [Mouse]
Predicted to enable RNA binding activity and helicase activity. Is expressed in central nervous system and retina. Orthologous to human DHX57 (DExH-box helicase 57). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dhx57 |
| Official Name | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Source:MGI Symbol;Acc:MGI:2147067] |
| Ensembl ID | ENSMUSG00000035051 |
| Bio databases IDs | |
| Aliases | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| Synonyms | AW494914, DDX57, DExH-box helicase 57 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dhx57 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UBA domain-like superfamily
- Helicase associated domain (HA2)
- Oligonucleotide/oligosaccharide-binding (OB)-fold
- CCCH-type zinc finger
- DEAD/DEAH box helicase
- helicase superfamily c-terminal domain
- Zinc finger C-x8-C-x5-C-x3-H type (and similar)
- protein binding
- Helicase conserved C-terminal domain
- zinc finger
- Helicase associated domain (HA2) Add an annotation
- RNA-binding, Nab2-type zinc finger
- RWD, DRWD, and ELF domain family
- N-terminal helicase domain of the DEAD-box helicase superfamily
- RWD domain
- zinc finger domain
- DEAD-like helicases superfamily
- P-loop containing Nucleoside Triphosphate Hydrolases
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dhx57 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- intracellular
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- RNA binding
- protein binding
- RNA helicase activity
- metal ion binding
- helicase activity