Psma7 Gene Summary [Rat]

Predicted to enable identical protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome core complex, alpha-subunit complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human PSMA7 (proteasome 20S subunit alpha 7). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Psma7
Official Name
proteasome 20S subunit alpha 7 [Source:RGD Symbol;Acc:61851]
Ensembl ID
ENSRNOG00000056853
Bio databases IDs NCBI: 29674 Ensembl: ENSRNOG00000056853
Aliases proteasome 20S subunit alpha 7
Synonyms 20S PROTEASOME alpha 7 subunit, 20S PROTEASOME α 7 subunit, 26s Proteasome alpha 1, 26s Proteasome α 1, C6, C6-I, HEL-S-276, HSPC, proteasome 20S subunit alpha 7, proteasome 20S subunit α 7, proteasome subunit alpha 7, proteasome subunit α 7, RC6-1, XAPC7
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Psma7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ntn_hydrolase
  • proteasome endopeptidase complex
  • Proteasome subunit A N-terminal signature
  • peptidase
  • Proteasome subunit A N-terminal signature Add an annotation
  • proteasome endopeptidase complex, archaeal, alpha subunit
  • protein binding
  • Proteasome subunit
  • identical protein binding

Pathways

Biological processes and signaling networks where the Psma7 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colon cancer
  • major depression
  • cataract
  • infection by HIV-1
regulated by
regulates
role in cell
  • cell death
  • survival

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • membrane fraction
  • Nucleus
  • cytosol
  • nucleoplasm
  • clastosomes
  • late endosomes
  • cytosolic fraction

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Psma7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteasomal ubiquitin-dependent protein catabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • extracellular vesicular exosome
  • cytoplasm
  • proteasome core complex
  • proteasome core complex, alpha-subunit complex
  • cytosol
  • proteasome complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.