Rsph1 Gene Summary [Rat]
Predicted to be involved in axoneme assembly and spermatid development. Predicted to be located in condensed nuclear chromosome and cytoskeleton. Predicted to be part of radial spoke head 1 and radial spoke head 3. Predicted to be active in motile cilium and nucleus. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma and primary ciliary dyskinesia 24. Orthologous to human RSPH1 (radial spoke head component 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rsph1 |
| Official Name | radial spoke head component 1 [Source:RGD Symbol;Acc:1307712] |
| Ensembl ID | ENSRNOG00000057862 |
| Bio databases IDs | |
| Aliases | radial spoke head component 1 |
| Synonyms | CT79, MCA, radial spoke head 1 homolog (Chlamydomonas), radial spoke head component 1, RSP44, RSPH10A, TSA2, TSGA2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rsph1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Membrane Occupation and Recognition Nexus motif
- MORN repeat
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- motile cilia
- Cytoplasm
- flagella
- axonemes
- fibrous sheath of sperm
- chromosome
- sperm tail
- sperm head
- outer dense fibers
- meiotic spindles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rsph1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- meiotic cell cycle
- spermatid development
- axoneme assembly
Cellular Component
Where in the cell the gene product is active
- outer dense fiber
- nucleus
- motile cilium
- radial spokehead
- cytosol
- meiotic spindle
- sperm flagellum
- condensed nuclear chromosome
Molecular Function
What the gene product does at the molecular level
- protein binding