NUDCD2 Gene Summary [Human]
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Located in cytosol; intercellular bridge; and mitotic spindle. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | NUDCD2 |
| Official Name | NudC domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30535] |
| Ensembl ID | ENSG00000170584 |
| Bio databases IDs | |
| Aliases | NudC domain containing 2 |
| Synonyms | NudC domain containing 2, NudCL2, RGD1307203, RIKEN CDNA 2700047N05 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NUDCD2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CS domain
- alpha-crystallin Hsps/p23-like
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- cytoplasmic bridges
- cytosol
- mitotic spindle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NUDCD2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein folding
Cellular Component
Where in the cell the gene product is active
- centrosome
- intercellular bridge
- microtubule cytoskeleton
- mitotic spindle
- cytoplasm
- spindle pole
- cytosol
- kinetochore
Molecular Function
What the gene product does at the molecular level
- protein binding
- unfolded protein binding