GeneGlobe ID: SBHS-025Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels

QuantiNova LNA PCR Focus Panel Human NFkB Signaling Pathway

QuantiNova LNA PCR Focus Panel
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Product Specification

Target List
NFκB Signaling
NFκB Signaling Ligands & Receptors​
CD27 (TNFRSF7), CD40 (TNFRSF5), CXCL8 (IL8), EGFR (ERBB1), F2R (PAR1), FASLG (TNFSF6), IL10, IL1A, IL1B, IL1R1, LTBR, NOD1 (CARD4), TLR1, TLR2, TLR3, TLR4, TLR6, TLR9, TNF, TNFRSF10A (TRAIL-R), TNFRSF10B (DR5), TNFRSF1A (TNFR1), TNFSF10 (TRAIL), TNFSF14
Signaling Downstream of NFκB​
BIRC2 (c-IAP1), FADD, IRAK1, IRAK2, IRF1, MYD88, RIPK1, TBK1, TICAM1 (TRIF), TICAM2 (TRAM), TNFAIP3, TRADD, TRAF2, TRAF3, TRAF6
Cytoplasmic Sequestering / Releasing of NFκB​
BCL3, CHUK (IKKα), IKBKB (IKKβ), IKBKE, IKBKG, NFKBIA (IκBα, MAD3), NFKBIB (TRIP9), NFKBIE
Transcription Factors​
NFKB1, NFKB2, REL, RELA, RELB
NFκB Responsive Genes
Immune Response​
CCL2 (MCP-1), CCL5 (RANTES), CSF1 (MCSF), CSF2 (GM-CSF), CSF3 (GCSF), CXCL8 (IL8), ICAM1, IFNA1, IFNG, LTA (TNFB), TNF
Apoptosis​
AGT, BCL2A1 (BFL1), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BIRC3 (c-IAP2)
Other Factors Involved in NFκB Pathway
Kinases​
AKT1, MAP3K1 (MEKK1), RAF1
Transcription Factors​
ATF1, EGR1, ELK1, FOS, JUN, STAT1
Other NFκB Signaling Genes​
BCL10, CARD11, CASP1 (ICE), CASP8 (FLICE), CFLAR (CASPER), HMOX1, MALT1, PSIP1, RHOA, TIMP1
Gene Resource List
Array Layout for PCR Plates
File Size: 153.27 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 153.4 KBLanguage: English

Resources

Quick-Start Protocols (1)
Safety Data Sheets (1)
Kit Handbooks (1)
Certificates of Analysis (1)
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