![Qiagen Logo](/assets//images/qiagen-logo.png)
You can accept or revoke the cookies used on this website at any time with the selection below or by adjusting your cookie settings. For complete details about our cookies, see our Cookie Policy.
The Tumor Necrosis Factor Receptor (TNFR) super family represents a growing family with over 20 members having been identified so far in mammalian cells. TNFα, a potent cytokine, elicits a broad spectrum of biologic responses. Members of the TNFR superfamily can send both survival and death signals to cells. TNF family members play important roles in various physiological and pathological processes, including cell proliferation, differentiation, apoptosis, modulation of immune responses and induction of inflammation. TNFα acts through two receptors, TNFR1 and TNFR2...