RANBP3 Gene Summary [Human]
This gene encodes a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | RANBP3 |
| Official Name | RAN binding protein 3 [Source:HGNC Symbol;Acc:HGNC:9850] |
| Ensembl ID | ENSG00000031823 |
| Bio databases IDs | |
| Aliases | RAN binding protein 3 |
| Synonyms | 2610024N24RIK, RAN binding protein 3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RANBP3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SMAD binding
- enzyme binding
- protein binding
- Pleckstrin homology-like domain
- Ran binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RANBP3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein export from nucleus
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nucleoplasm
- nuclear pore
Molecular Function
What the gene product does at the molecular level
- protein binding
- GTPase activator activity
- R-SMAD binding