ZC3H15 Gene Summary [Human]
Enables RNA binding activity and cadherin binding activity. Involved in positive regulation of GTPase activity. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZC3H15 |
| Official Name | zinc finger CCCH-type containing 15 [Source:HGNC Symbol;Acc:HGNC:29528] |
| Ensembl ID | ENSG00000065548 |
| Bio databases IDs | |
| Aliases | zinc finger CCCH-type containing 15, likely ortholog of mouse immediate early response, erythropoietin 4 |
| Synonyms | 1700006A17Rik, 1810012H02Rik, 2610312B22Rik, DFRP1, FM22, HT010, Ierepo4, Immediate early response, erythropoietin 4, LEREPO4, MSTP012, zinc finger CCCH-type containing 15 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZC3H15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc finger
- RNA-binding, Nab2-type zinc finger
- CCCH-type zinc finger
- Zinc finger C-x8-C-x5-C-x3-H type (and similar)
- protein binding
- DRG Family Regulatory Proteins, Tma46
- zinc finger domain
- translation regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- head and neck neoplasia
- chronic kidney disease
- prostate cancer
- organismal death
- prostatic intraepithelial neoplasm
- prostatic intraepithelial neoplasia
- glioblastoma cancer
- glioblastoma
role in cell
- proliferation
- expression in
- migration
- invasion by
- stabilization in
- ubiquitination in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZC3H15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- cytokine-mediated signaling pathway
- positive regulation of GTPase activity
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- metal ion binding
- cadherin binding