KRR1 Gene Summary [Human]

Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in chromosome; intercellular bridge; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
KRR1
Official Name
KRR1 small subunit processome component homolog [Source:HGNC Symbol;Acc:HGNC:5176]
Ensembl ID
ENSG00000111615
Bio databases IDs NCBI: 11103 Ensembl: ENSG00000111615
Aliases KRR1 small subunit processome component homolog
Synonyms 2610511F02Rik, D10Ertd773e, HRB2, KRR1 small subunit processome component homolog, KRR1, small subunit processome component homolog, KRR1, small subunit (SSU) processome component, homolog (yeast), RIP-1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KRR1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Krr1 KH1 domain
  • K homology (KH) RNA-binding domain, type I
  • arCOG04150 universal archaeal KH domain protein
  • protein binding
  • K homology RNA-binding domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-small cell lung cancer
regulated by
role in cell
  • processing in
  • translation in
  • cellular reprogramming
  • pluripotency

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • pre-ribosome
  • Cytoplasm
  • cytoplasmic bridges
  • chromosome
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human KRR1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal small subunit biogenesis
  • rRNA processing

Cellular Component

Where in the cell the gene product is active
  • small-subunit processome
  • intercellular bridge
  • cytoplasm
  • membrane
  • chromosome
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.