CFAP20 Gene Summary [Human]
Enables RNA binding activity. Involved in several processes, including positive regulation of feeding behavior; protein polyglutamylation; and regulation of cell motility. Located in centriole; ciliary basal body; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CFAP20 |
| Official Name | cilia and flagella associated protein 20 [Source:HGNC Symbol;Acc:HGNC:29523] |
| Ensembl ID | ENSG00000070761 |
| Bio databases IDs | |
| Aliases | cilia and flagella associated protein 20, functional spliceosome-associated protein 23, flagellar associated protein 20 homolog (Chlamydomonas) |
| Synonyms | 2600014O15Rik, BUG22, C16orf80, cilia and flagella associated protein 20, EVORF, fSAP23, GTL3, T10-2A2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CFAP20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CFA20 domain
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- basal bodies
- centriole
- axonemes
- spliceosomes
- nucleoplasm
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CFAP20 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein polyglutamylation
- cilium morphogenesis
- regulation of cilium beat frequency involved in ciliary motility
- positive regulation of feeding behavior
- positive regulation of cell motility
Cellular Component
Where in the cell the gene product is active
- axonemal microtubule
- motile cilium
- extracellular vesicular exosome
- centriole
- cilium basal body
- cilium
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding