RBM7 Gene Summary [Human]

Enables 14-3-3 protein binding activity; pre-mRNA intronic binding activity; and snRNA binding activity. Involved in snRNA catabolic process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
RBM7
Official Name
RNA binding motif protein 7 [Source:HGNC Symbol;Acc:HGNC:9904]
Ensembl ID
ENSG00000076053
Bio databases IDs NCBI: 10179 Ensembl: ENSG00000076053
Aliases RNA binding motif protein 7
Synonyms 1200007M24Rik, 1500011D06RIK, RNA binding motif protein 7
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RBM7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • snRNA binding
  • RNA recognition motif (RRM) superfamily
  • RNA recognition motif
  • protein binding
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • nonalcoholic fatty liver disease
  • bleomycin-induced pulmonary fibrosis
  • pulmonary fibrosis
  • short telomere syndrome
  • infection by HIV-1
regulated by
role in cell
  • apoptosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RBM7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • meiotic cell cycle
  • regulation of alternative nuclear mRNA splicing, via spliceosome
  • snRNA catabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • pre-mRNA intronic binding
  • protein binding
  • RNA binding
  • single-stranded RNA binding
  • snRNA binding
  • 14-3-3 protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.