P2RY10 Gene Summary [Human]
The protein encoded by this gene belongs to the family of G-protein coupled receptors that are preferentially activated by adenosine and uridine nucleotides. There is a pseudogene for this gene nearby on chromosome X. Multiple alternatively spliced transcripts have been observed. [provided by RefSeq, Apr 2016]
Details
| Type | Processed Transcript |
| Official Symbol | P2RY10 |
| Official Name | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] |
| Ensembl ID | ENSG00000078589 |
| Bio databases IDs | |
| Aliases | P2Y receptor family member 10 |
| Synonyms | 5830408N17Rik, LPS2, LYPSR2, P2Y10, P2Y receptor family member 10, purinergic receptor P2Y, G-protein coupled 10, RGD1561912 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human P2RY10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Cholecystokinin A receptor, N-terminal
- 7 transmembrane receptor (rhodopsin family)
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the P2RY10 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- sepsis
- colorectal cancer
- experimental autoimmune encephalomyelitis
- delayed hypersensitive reaction
- septic shock
- TNBS-induced colitis
- insulin-dependent diabetes mellitus
- infection by vesicular stomatitis virus
role in cell
- activation in
- migration
- polarization
- shedding in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human P2RY10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of Rho protein signal transduction
- phospholipase C-activating G-protein coupled receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity