BPIFB2 Gene Summary [Human]
This gene encodes a member of the lipid transfer/lipopolysaccharide binding protein (LT/LBP) gene family. It is highly expressed in hypertrophic tonsils. This gene and three other members of the LT/LBP gene family form a cluster on the long arm of chromosome 20. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | BPIFB2 |
| Official Name | BPI fold containing family B member 2 [Source:HGNC Symbol;Acc:HGNC:16177] |
| Ensembl ID | ENSG00000078898 |
| Bio databases IDs | |
| Aliases | BPI fold containing family B member 2 |
| Synonyms | 2310034L21Rik, 2310069A01Rik, BPI fold containing family B member 2, BPI fold containing family B, member 2, BPIL1, C20orf184, dJ726C3.2, LPLUNC2, RYSR |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human BPIFB2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- BPI
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- endoplasmic reticulum lumen
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human BPIFB2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- extracellular vesicular exosome
- extracellular region
Molecular Function
What the gene product does at the molecular level
- lipid binding