TUT7 Gene Summary [Human]
Enables RNA uridylyltransferase activity and miRNA binding activity. Involved in RNA metabolic process and negative regulation of transposition, RNA-mediated. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TUT7 |
| Official Name | terminal uridylyl transferase 7 [Source:HGNC Symbol;Acc:HGNC:25817] |
| Ensembl ID | ENSG00000083223 |
| Bio databases IDs | |
| Aliases | terminal uridylyl transferase 7, TUTase7 |
| Synonyms | 6030448M23RIK, FLJ13409, MGC38585, PAPD6, TENT3B, terminal uridylyl transferase 7, ZCCHC6 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TUT7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc knuckle
- zinc finger
- Cid1 family poly A polymerase
- Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins
- RNA uridylyltransferase
- TUTase nucleotidyltransferase domain
- nucleotidyltransferase
- enzyme
- protein binding
- Unstructured region 4 on terminal uridylyltransferase 7
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TUT7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA 3' uridylation
- oocyte maturation
- pre-miRNA processing
- histone mRNA catabolic process
- RNA 3'-end processing
- miRNA metabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- miRNA binding
- RNA uridylyltransferase activity
- zinc ion binding
- RNA binding
- protein binding
- uridylyltransferase activity