Tut7 Gene Summary [Mouse]
Enables uridylyltransferase activity. Involved in oocyte maturation and polyuridylation-dependent mRNA catabolic process. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including autopod; early conceptus; genitourinary system; sensory organ; and skeleton. Orthologous to human TUT7 (terminal uridylyl transferase 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tut7 |
| Official Name | terminal uridylyl transferase 7 [Source:MGI Symbol;Acc:MGI:2387179] |
| Ensembl ID | ENSMUSG00000035248 |
| Bio databases IDs | |
| Aliases | terminal uridylyl transferase 7 |
| Synonyms | 6030448M23RIK, FLJ13409, MGC38585, PAPD6, TENT3B, terminal uridylyl transferase 7, ZCCHC6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tut7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc knuckle
- zinc finger
- Cid1 family poly A polymerase
- Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins
- RNA uridylyltransferase
- TUTase nucleotidyltransferase domain
- nucleotidyltransferase
- enzyme
- protein binding
- Unstructured region 4 on terminal uridylyltransferase 7
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tut7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA 3' uridylation
- oocyte maturation
- pre-miRNA processing
- histone mRNA catabolic process
- RNA 3'-end processing
- miRNA metabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- miRNA binding
- RNA uridylyltransferase activity
- zinc ion binding
- RNA binding
- protein binding
- uridylyltransferase activity