TXLNA Gene Summary [Human]

Predicted to enable syntaxin binding activity. Predicted to be involved in exocytosis. Predicted to act upstream of or within B cell activation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TXLNA
Official Name
taxilin alpha [Source:HGNC Symbol;Acc:HGNC:30685]
Ensembl ID
ENSG00000084652
Bio databases IDs NCBI: 200081 Ensembl: ENSG00000084652
Aliases taxilin alpha
Synonyms 2600010N21Rik, DKFZp451J0118, IL-14, taxilin alpha, taxilin α, TXLN
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TXLNA often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Myosin-like coiled-coil protein
  • protein binding
  • cytokine

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • cancer
  • systemic lupus erythematosus
  • lymphomagenesis
  • B cell cancer
  • B-cell neoplasia
  • hematologic cancer
  • lymphoid cancer
  • hematological neoplasia
  • lymphatic neoplasia
  • lymphocytic cancer
regulated by
regulates
  • Immunoglobulin
  • LTA
  • diacylglycerol
  • CXCR6
  • IgG2a
role in cell
  • proliferation
  • activation
  • growth
  • stimulation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TXLNA gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • B cell activation
  • exocytosis

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • membrane
  • cytosol
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • syntaxin binding

Gene-Specific Assays for Results You Can Trust

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