Txlna Gene Summary [Mouse]
Predicted to enable syntaxin binding activity. Acts upstream of or within B cell activation. Predicted to be located in cytoplasm. Is expressed in brain; metanephros; oviduct; spinal cord; and testis. Orthologous to human TXLNA (taxilin alpha). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Txlna |
| Official Name | taxilin alpha [Source:MGI Symbol;Acc:MGI:105968] |
| Ensembl ID | ENSMUSG00000053841 |
| Bio databases IDs | |
| Aliases | taxilin alpha |
| Synonyms | 2600010N21Rik, DKFZp451J0118, IL-14, taxilin alpha, taxilin α, TXLN |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Txlna often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Myosin-like coiled-coil protein
- protein binding
- cytokine
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cancer
- systemic lupus erythematosus
- lymphomagenesis
- B cell cancer
- B-cell neoplasia
- hematologic cancer
- lymphoid cancer
- hematological neoplasia
- lymphatic neoplasia
- lymphocytic cancer
role in cell
- proliferation
- activation
- growth
- stimulation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Txlna gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- B cell activation
- exocytosis
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
- cytosol
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- syntaxin binding