SUSD2 Gene Summary [Human]
Involved in negative regulation of cell cycle G1/S phase transition and negative regulation of cell division. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SUSD2 |
| Official Name | sushi domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30667] |
| Ensembl ID | ENSG00000099994 |
| Bio databases IDs | |
| Aliases | sushi domain containing 2 |
| Synonyms | 1200011D11RIK, BK65A6.2, sushi domain containing 2, W5C5 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SUSD2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CCP
- von Willebrand factor type D domain
- AMOP domain
- protein binding
- von Willebrand factor (vWF) type D domain
- Sushi repeat (SCR repeat)
- Somatomedin B domain
- SUSHI repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SUSD2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of cell division
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding