Susd2 Gene Summary [Mouse]
Predicted to be involved in negative regulation of cell cycle G1/S phase transition and negative regulation of cell division. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in ganglia; hindbrain; urinary system; and ventral grey horn. Orthologous to human SUSD2 (sushi domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Susd2 |
| Official Name | sushi domain containing 2 [Source:MGI Symbol;Acc:MGI:1918983] |
| Ensembl ID | ENSMUSG00000006342 |
| Bio databases IDs | |
| Aliases | sushi domain containing 2 |
| Synonyms | 1200011D11RIK, BK65A6.2, sushi domain containing 2, W5C5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Susd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CCP
- von Willebrand factor type D domain
- AMOP domain
- protein binding
- von Willebrand factor (vWF) type D domain
- Sushi repeat (SCR repeat)
- Somatomedin B domain
- SUSHI repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Susd2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of cell division
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding