ANKRD54 Gene Summary [Human]

Predicted to enable protein kinase regulator activity. Predicted to be involved in positive regulation of erythrocyte differentiation; regulation of intracellular signal transduction; and regulation of protein kinase activity. Predicted to act upstream of or within nucleocytoplasmic transport. Predicted to be located in midbody. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
ANKRD54
Official Name
ankyrin repeat domain 54 [Source:HGNC Symbol;Acc:HGNC:25185]
Ensembl ID
ENSG00000100124
Bio databases IDs NCBI: 129138 Ensembl: ENSG00000100124
Aliases ankyrin repeat domain 54, Lyn-interacting ankyrin repeat protein
Synonyms ankyrin repeat domain 54, C730048E16Rik, EST1068184, EST475269, LIAR, RGD1309552
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ANKRD54 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • Ankyrin repeats (many copies)
  • binding protein
  • Ankyrin repeats (3 copies)
  • protein kinase regulator
  • protein binding
  • Ankyrin repeat
  • ankyrin repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • midbody

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ANKRD54 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nucleocytoplasmic transport
  • regulation of protein kinase activity
  • positive regulation of erythrocyte differentiation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • midbody

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • protein kinase regulator activity

Gene-Specific Assays for Results You Can Trust

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