Ankrd54 Gene Summary [Mouse]

Enables protein kinase regulator activity. Acts upstream of or within several processes, including nucleocytoplasmic transport; positive regulation of erythrocyte differentiation; and regulation of protein kinase activity. Located in cytoplasm; midbody; and nucleus. Is expressed in several structures, including branchial arch; central nervous system; gut; immune system; and limb bud. Orthologous to human ANKRD54 (ankyrin repeat domain 54). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ankrd54
Official Name
ankyrin repeat domain 54 [Source:MGI Symbol;Acc:MGI:2444209]
Ensembl ID
ENSMUSG00000033055
Bio databases IDs NCBI: 223690 Ensembl: ENSMUSG00000033055
Aliases ankyrin repeat domain 54
Synonyms ankyrin repeat domain 54, C730048E16Rik, EST1068184, EST475269, LIAR, RGD1309552
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ankrd54 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • Ankyrin repeats (many copies)
  • binding protein
  • Ankyrin repeats (3 copies)
  • protein kinase regulator
  • protein binding
  • Ankyrin repeat
  • ankyrin repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • midbody

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ankrd54 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nucleocytoplasmic transport
  • regulation of protein kinase activity
  • positive regulation of erythrocyte differentiation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • midbody

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • protein kinase regulator activity