PNPLA5 Gene Summary [Human]
This gene is a member of the patatin-like phospholipase family; its encoded protein has been shown to inhibit transacylation. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]
Details
| Type | Protein Coding |
| Official Symbol | PNPLA5 |
| Official Name | patatin like phospholipase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:24888] |
| Ensembl ID | ENSG00000100341 |
| Bio databases IDs | |
| Aliases | patatin like phospholipase domain containing 5 |
| Synonyms | 4833426H19Rik, dJ388M5, dJ388M5.4, GS2L, patatin-like phospholipase domain containing 5, RGD1307495 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PNPLA5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Patatins and Phospholipases
- enzyme
- protein binding
- triacylglycerol lipase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PNPLA5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lipid homeostasis
- triglyceride catabolic process
Cellular Component
Where in the cell the gene product is active
- lipid particle
- cytoplasm
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- triglyceride lipase activity