Pnpla5 Gene Summary [Mouse]
Predicted to enable triacylglycerol lipase activity. Predicted to be involved in lipid homeostasis and triglyceride catabolic process. Predicted to be active in cytoplasm; lipid droplet; and membrane. Orthologous to human PNPLA5 (patatin like phospholipase domain containing 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pnpla5 |
| Official Name | patatin-like phospholipase domain containing 5 [Source:MGI Symbol;Acc:MGI:1923022] |
| Ensembl ID | ENSMUSG00000018868 |
| Bio databases IDs | |
| Aliases | patatin-like phospholipase domain containing 5 |
| Synonyms | 4833426H19Rik, dJ388M5, dJ388M5.4, GS2L, patatin-like phospholipase domain containing 5, RGD1307495 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pnpla5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Patatins and Phospholipases
- enzyme
- protein binding
- triacylglycerol lipase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pnpla5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lipid homeostasis
- triglyceride catabolic process
Cellular Component
Where in the cell the gene product is active
- lipid particle
- cytoplasm
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- triglyceride lipase activity