LMF1 Gene Summary [Human]
Involved in triglyceride metabolic process. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Implicated in familial lipase maturation factor 1 deficiency. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | LMF1 |
| Official Name | lipase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:14154] |
| Ensembl ID | ENSG00000103227 |
| Bio databases IDs | |
| Aliases | lipase maturation factor 1 |
| Synonyms | 2400010G15RIK, AW822050, C16ORF26, Cld, HMFN1876, JFP11, lipase maturation factor 1, LOC650392, RGD1310180, RP11 161M62, TMEM112, TMEM112A |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LMF1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Lipase maturation factor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hypertriglyceridemia
- glioma
- glioma formation
- combined lipase deficiency
- Turner syndrome
- non-insulin-dependent diabetes mellitus
- malignant glioma
- glioma cancer
- heart failure
- Klinefelter syndrome
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LMF1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- triglyceride metabolic process
- protein maturation
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane