CAPN15 Gene Summary [Human]

This gene encodes a protein containing zinc-finger-like repeats and a calpain-like protease domain. The encoded protein may function as a transcription factor, RNA-binding protein, or in protein-protein interactions during visual system development. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
CAPN15
Official Name
calpain 15 [Source:HGNC Symbol;Acc:HGNC:11182]
Ensembl ID
ENSG00000103326
Bio databases IDs NCBI: 6650 Ensembl: ENSG00000103326
Aliases calpain 15
Synonyms calpain 15, OGIN, SOLH
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CAPN15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Calpain family cysteine protease
  • Zn-finger in Ran binding protein and others
  • peptidase
  • protein binding
  • zinc finger domain
  • CysPc

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • anophthalmia
  • oculogastrointestinal neurodevelopmental syndrome
  • Wilms tumor
  • Wilms tumorigenesis
  • suicide attempt
  • microphthalmia
  • cataract disease
  • prostate cancer
  • tinnitus
regulates
  • lipid
role in cell
  • accumulation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CAPN15 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • calcium-dependent cysteine-type endopeptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.