Capn15 Gene Summary [Mouse]
Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytoplasm. Is expressed in brain; genitourinary system; and retina ganglion cell layer. Orthologous to human CAPN15 (calpain 15). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Capn15 |
| Official Name | calpain 15 [Source:MGI Symbol;Acc:MGI:1355075] |
| Ensembl ID | ENSMUSG00000037326 |
| Bio databases IDs | |
| Aliases | calpain 15 |
| Synonyms | calpain 15, OGIN, SOLH |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Capn15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calpain family cysteine protease
- Zn-finger in Ran binding protein and others
- peptidase
- protein binding
- zinc finger domain
- CysPc
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- anophthalmia
- oculogastrointestinal neurodevelopmental syndrome
- Wilms tumor
- Wilms tumorigenesis
- suicide attempt
- microphthalmia
- cataract disease
- prostate cancer
- tinnitus
regulates
- lipid
role in cell
- accumulation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Capn15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- calcium-dependent cysteine-type endopeptidase activity