RPAP1 Gene Summary [Human]
This protein forms part of the RNA polymerase II (RNAPII) enzyme complex and may recruit RNAPII to chromatin through its interaction with acetylated histones. [provided by RefSeq, Jul 2012]
Details
| Type | Retained Intron |
| Official Symbol | RPAP1 |
| Official Name | RNA polymerase II associated protein 1 [Source:HGNC Symbol;Acc:HGNC:24567] |
| Ensembl ID | ENSG00000103932 |
| Bio databases IDs | |
| Aliases | RNA polymerase II associated protein 1 |
| Synonyms | 1190005L06Rik, A730023M06Rik, mKIAA1403, RNA polymerase II associated protein 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RPAP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RPAP1-like, C-terminal
- protein binding
- RPAP1-like, N-terminal
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RPAP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- DNA-directed RNA polymerase complex
Molecular Function
What the gene product does at the molecular level
- DNA binding
- nucleotidyltransferase activity
- protein binding