EDRF1 Gene Summary [Human]
This gene may play a role in erythroid cell differentiation. The encoded protein inhibits DNA binding of the erythroid transcription factor GATA-1 and may regulate the expression of alpha-globin and gamma-globin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | EDRF1 |
| Official Name | erythroid differentiation regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:24640] |
| Ensembl ID | ENSG00000107938 |
| Bio databases IDs | |
| Aliases | erythroid differentiation regulatory factor 1, erythroid differentiation-related factor 1 |
| Synonyms | 2700050L05Rik, AU022667, C10orf137, erythroid differentiation regulatory factor 1, RGD1306820 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EDRF1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human EDRF1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding