ODAM Gene Summary [Human]
Involved in several processes, including positive regulation of GTPase activity; positive regulation of epithelial cell proliferation involved in wound healing; and positive regulation of macromolecule metabolic process. Located in several cellular components, including extracellular space; mitotic spindle; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ODAM |
| Official Name | odontogenic, ameloblast associated [Source:HGNC Symbol;Acc:HGNC:26043] |
| Ensembl ID | ENSG00000109205 |
| Bio databases IDs | |
| Aliases | odontogenic, ameloblast associated |
| Synonyms | 2310011G06Rik, APIN, odontogenic, ameloblast associated, odontogenic, ameloblast asssociated |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ODAM often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Odontogenic ameloblast-associated family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm
- cell periphery
- Nucleus
- cytosol
- nucleoplasm
- mitotic spindle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ODAM gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inflammatory response
- regulation of actin cytoskeleton organization
- positive regulation of gene expression
- positive regulation of epithelial cell proliferation involved in wound healing
- positive regulation of protein phosphorylation
- odontogenesis of dentin-containing tooth
- positive regulation of GTPase activity
- biomineral tissue development
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular space
- mitotic spindle
- cytoplasm
- cytosol
- extracellular region
- nucleoplasm
- cell periphery
Molecular Function
What the gene product does at the molecular level
- protein binding