SRSF11 Gene Summary [Human]

This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010]

Details

Type
Protein Coding
Official Symbol
SRSF11
Official Name
serine and arginine rich splicing factor 11 [Source:HGNC Symbol;Acc:HGNC:10782]
Ensembl ID
ENSG00000116754
Bio databases IDs NCBI: 9295 Ensembl: ENSG00000116754
Aliases serine and arginine rich splicing factor 11, SR splicing factor 11
Synonyms 0610009J05Rik, 2610019N13Rik, dJ677H15.2, NET2, p54, serine and arginine-rich splicing factor 11, SFRS11
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SRSF11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA recognition motif (RRM) superfamily
  • RNA recognition motif
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • chronic obstructive pulmonary disease
  • myopia
  • primary antiphospholipid antibody syndrome
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • spliceosomes
  • nucleoplasm
  • nuclear speckles
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SRSF11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • RNA splicing
  • mRNA processing

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nuclear speck
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.