ADGB Gene Summary [Human]
Predicted to enable calcium-dependent cysteine-type endopeptidase activity; heme binding activity; and oxygen binding activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | ADGB |
| Official Name | androglobin [Source:HGNC Symbol;Acc:HGNC:21212] |
| Ensembl ID | ENSG00000118492 |
| Bio databases IDs | |
| Aliases | androglobin |
| Synonyms | 9130014G24Rik, androglobin, C6orf103, CAPN16, RGD1564259 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ADGB often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- IQ (isoleucine-glutamine) motif containing G and D (IQCG and IQCD)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- sperm annulus
- sperm midpiece
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ADGB gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatid development
- proteolysis
Cellular Component
Where in the cell the gene product is active
- sperm midpiece
- sperm annulus
Molecular Function
What the gene product does at the molecular level
- oxygen binding
- metal ion binding
- calcium-dependent cysteine-type endopeptidase activity
- heme binding