Adgb Gene Summary [Mouse]
Predicted to enable several functions, including calcium-dependent cysteine-type endopeptidase activity; heme binding activity; and oxygen binding activity. Involved in spermatid development. Located in sperm annulus and sperm midpiece. Is expressed in lung. Orthologous to human ADGB (androglobin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Adgb |
| Official Name | androglobin [Source:MGI Symbol;Acc:MGI:3605549] |
| Ensembl ID | ENSMUSG00000050994 |
| Bio databases IDs | |
| Aliases | androglobin |
| Synonyms | 9130014G24Rik, androglobin, C6orf103, CAPN16, RGD1564259 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adgb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- IQ (isoleucine-glutamine) motif containing G and D (IQCG and IQCD)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- sperm annulus
- sperm midpiece
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Adgb gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatid development
- proteolysis
Cellular Component
Where in the cell the gene product is active
- sperm midpiece
- sperm annulus
Molecular Function
What the gene product does at the molecular level
- oxygen binding
- metal ion binding
- calcium-dependent cysteine-type endopeptidase activity
- heme binding