RBM19 Gene Summary [Human]

This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009]

Details

Type
Processed Transcript
Official Symbol
RBM19
Official Name
RNA binding motif protein 19 [Source:HGNC Symbol;Acc:HGNC:29098]
Ensembl ID
ENSG00000122965
Bio databases IDs NCBI: 9904 Ensembl: ENSG00000122965
Aliases RNA binding motif protein 19
Synonyms 1200009A02Rik, KIAA0682, LOC687727, Mrd1, NPO, RNA binding motif protein 19
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RBM19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ELAV/HuD family splicing factor
  • RNA recognition motif (RRM) superfamily
  • RNA recognition motif

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • sporadic amyotrophic lateral sclerosis
  • parasitosis
  • productive infection by HIV-1
regulated by
role in cell
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RBM19 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of embryonic development
  • nuclear mRNA splicing, via spliceosome

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • nuclear speck
  • membrane
  • chromosome
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.