BAIAP2L2 Gene Summary [Human]
The protein encoded by this gene binds phosphoinositides and promotes the formation of planar or curved membrane structures. The encoded protein is found in RAB13-positive vesicles and at intercellular contacts with the plasma membrane. [provided by RefSeq, Dec 2012]
Details
| Type | Retained Intron |
| Official Symbol | BAIAP2L2 |
| Official Name | BAR/IMD domain containing adaptor protein 2 like 2 [Source:HGNC Symbol;Acc:HGNC:26203] |
| Ensembl ID | ENSG00000128298 |
| Bio databases IDs | |
| Aliases | BAR/IMD domain containing adaptor protein 2 like 2, planar intestinal- and kidney-specific BAR domain protein |
| Synonyms | BAI1-associated protein 2-like 2, BAR/IMD domain containing adaptor protein 2 like 2, LOC100364174, RGD1308786 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human BAIAP2L2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phospholipid binding
- IRSp53/MIM homology domain
- Bin/Amphiphysin/Rvs domain
- identical protein binding
- Src Homology 3 domain superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intercellular junctions
- cytosol
- vesicle membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human BAIAP2L2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- membrane organization
- actin crosslink formation
- plasma membrane organization
- positive regulation of actin filament polymerization
- actin filament bundle assembly
Cellular Component
Where in the cell the gene product is active
- cell-cell contact zone
- cytoplasmic vesicle membrane
- vesicle membrane
- cytosol
- clathrin complex
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- phospholipid binding