Baiap2l2 Gene Summary [Rat]

Predicted to enable identical protein binding activity and phospholipid binding activity. Predicted to be involved in actin filament organization; membrane organization; and positive regulation of actin filament polymerization. Predicted to be located in cell-cell contact zone and vesicle membrane. Predicted to be part of clathrin complex. Predicted to be active in cytosol and nucleoplasm. Orthologous to human BAIAP2L2 (BAR/IMD domain containing adaptor protein 2 like 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Baiap2l2
Official Name
BAI1-associated protein 2-like 2 [Source:RGD Symbol;Acc:1595091]
Ensembl ID
ENSRNOG00000012215
Bio databases IDs NCBI: 685357 Ensembl: ENSRNOG00000012215
Aliases BAI1-associated protein 2-like 2
Synonyms BAI1-associated protein 2-like 2, BAR/IMD domain containing adaptor protein 2 like 2, LOC100364174, RGD1308786
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Baiap2l2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • phospholipid binding
  • IRSp53/MIM homology domain
  • Bin/Amphiphysin/Rvs domain
  • identical protein binding
  • Src Homology 3 domain superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • liver cancer
  • hepatocellular carcinoma
  • age-related hearing loss
  • hearing loss
  • tinnitus
role in cell
  • migration
  • organization
  • invasion by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intercellular junctions
  • cytosol
  • vesicle membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Baiap2l2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • membrane organization
  • actin crosslink formation
  • plasma membrane organization
  • positive regulation of actin filament polymerization
  • actin filament bundle assembly

Cellular Component

Where in the cell the gene product is active
  • cell-cell contact zone
  • cytoplasmic vesicle membrane
  • vesicle membrane
  • cytosol
  • clathrin complex
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • phospholipid binding

Gene-Specific Assays for Results You Can Trust

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