PIMREG Gene Summary [Human]
Predicted to be involved in cell division. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PIMREG |
| Official Name | PICALM interacting mitotic regulator [Source:HGNC Symbol;Acc:HGNC:25483] |
| Ensembl ID | ENSG00000129195 |
| Bio databases IDs | |
| Aliases | PICALM interacting mitotic regulator, CALM interacting protein expressed in thymus and spleen, Regulator of chromosome segregation protein 1 |
| Synonyms | 2610008F03Rik, 6720460F02Rik, CATS, FAM64A, PICALM interacting mitotic regulator, RCS1, RGD1308747 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PIMREG often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Regulator of chromosome segregation 1
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- prostate cancer
- breast cancer
- organismal death
- experimental autoimmune encephalomyelitis
- azoxymethane/dextran sodium sulfate induced colorectal cancer
- dextran sodium sulfate-induced colitis
role in cell
- proliferation
- migration
- apoptosis
- cell cycle progression
- formation
- formation in
- binding in
- activation in
- transcription in
- upregulation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PIMREG gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
Cellular Component
Where in the cell the gene product is active
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding