SULT4A1 Gene Summary [Human]
This gene encodes a member of the sulfotransferase family. The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. Polymorphisms in this gene may be associated with susceptibility to schizophrenia. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | SULT4A1 |
| Official Name | sulfotransferase family 4A member 1 [Source:HGNC Symbol;Acc:HGNC:14903] |
| Ensembl ID | ENSG00000130540 |
| Bio databases IDs | |
| Aliases | sulfotransferase family 4A member 1 |
| Synonyms | 2400007A17Rik, BR-STL, BR-STL-1, DJ388M5.3, hBR-STL-1, mBR-STL, NST, ST4A1, sulfotransferase family 4A member 1, sulfotransferase family 4A, member 1, sulphotransferase family 4A member 1, sulphotransferase family 4A, member 1, Sulta41, SULTX3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SULT4A1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- sulfotransferase
- Sulfotransferase domain
- enzyme
- protein binding
- identical protein binding
- Sulfotransferase family
Pathways
Biological processes and signaling networks where the SULT4A1 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SULT4A1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- steroid metabolic process
- sulfation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- sulfotransferase activity