ADAMDEC1 Gene Summary [Human]
This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during dendritic cells maturation. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | ADAMDEC1 |
| Official Name | ADAM like decysin 1 [Source:HGNC Symbol;Acc:HGNC:16299] |
| Ensembl ID | ENSG00000134028 |
| Bio databases IDs | |
| Aliases | ADAM like decysin 1 |
| Synonyms | 2210414L24Rik, ADAM-LIKE, ADAM like decysin 1, ADAM-like, decysin 1, Dcsn, M12.219 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ADAMDEC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Reprolysin family propeptide
- ZnMc
- catalytic domain
- Metallo-peptidase family M12B Reprolysin-like
- peptidase
- Reprolysin (M12B) family zinc metalloprotease
Pathways
Biological processes and signaling networks where the ADAMDEC1 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- glioblastoma
- glioblastoma cancer
- Langerhans cell histiocytosis
- psoriasis
- organismal death
- aortic valve calcification
- HER2 negative hormone receptor negative breast cancer
- prostate cancer
- colitis
- eosinophilic esophagitis
role in cell
- expression in
- colony formation by
- proliferation
- number
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ADAMDEC1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- immune response
- negative regulation of cell adhesion
- proteolysis
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- metalloendopeptidase activity