KATNBL1 Gene Summary [Human]
Predicted to enable microtubule binding activity. Involved in positive regulation of cytoskeleton organization. Located in several cellular components, including cleavage furrow; mitotic spindle pole; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | KATNBL1 |
| Official Name | katanin regulatory subunit B1 like 1 [Source:HGNC Symbol;Acc:HGNC:26199] |
| Ensembl ID | ENSG00000134152 |
| Bio databases IDs | |
| Aliases | katanin regulatory subunit B1 like 1 |
| Synonyms | 2410042D21Rik, C15orf29, katanin p80 subunit B like 1, katanin regulatory subunit B1 like 1, LOC687904, NEWGENE 1582771 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KATNBL1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- con80 domain of Katanin
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- midbody
- nucleoplasm
- nucleoli
- spindle pole
- cleavage furrow
- mitotic spindle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human KATNBL1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of cytoskeleton organization
- cytoplasmic microtubule organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- microtubule cytoskeleton
- mitotic spindle
- katanin complex
- cleavage furrow
- cytoplasm
- midbody
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule binding