Katnbl1 Gene Summary [Mouse]

Predicted to enable microtubule binding activity. Predicted to be involved in cytoplasmic microtubule organization and positive regulation of cytoskeleton organization. Predicted to be located in several cellular components, including cleavage furrow; midbody; and mitotic spindle pole. Predicted to be part of katanin complex. Predicted to be active in nucleolus. Orthologous to human KATNBL1 (katanin regulatory subunit B1 like 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Katnbl1
Official Name
katanin p80 subunit B like 1 [Source:MGI Symbol;Acc:MGI:1919675]
Ensembl ID
ENSMUSG00000027132
Bio databases IDs NCBI: 72425 Ensembl: ENSMUSG00000027132
Aliases katanin p80 subunit B like 1
Synonyms 2410042D21Rik, C15orf29, katanin p80 subunit B like 1, katanin regulatory subunit B1 like 1, LOC687904, NEWGENE 1582771
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Katnbl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • con80 domain of Katanin
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • midbody
  • nucleoplasm
  • nucleoli
  • spindle pole
  • cleavage furrow
  • mitotic spindle

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Katnbl1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of cytoskeleton organization
  • cytoplasmic microtubule organization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • microtubule cytoskeleton
  • mitotic spindle
  • katanin complex
  • cleavage furrow
  • cytoplasm
  • midbody
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • microtubule binding

Gene-Specific Assays for Results You Can Trust

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