RELCH Gene Summary [Human]
Involved in intracellular cholesterol transport. Located in recycling endosome and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RELCH |
| Official Name | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing [Source:HGNC Symbol;Acc:HGNC:29289] |
| Ensembl ID | ENSG00000134444 |
| Bio databases IDs | |
| Aliases | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing |
| Synonyms | 2310035C23Rik, 6430401N10, HsT3308, HsT885, KIAA1468, mKIAA1468, RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing, RGD1307235 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RELCH often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- LisH
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- trans Golgi network
- recycling endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RELCH gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- intracellular cholesterol transport
Cellular Component
Where in the cell the gene product is active
- trans-Golgi network
- recycling endosome