URB2 Gene Summary [Human]
Predicted to be involved in ribosome biogenesis. Located in aggresome; midbody; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | URB2 |
| Official Name | URB2 ribosome biogenesis homolog [Source:HGNC Symbol;Acc:HGNC:28967] |
| Ensembl ID | ENSG00000135763 |
| Bio databases IDs | |
| Aliases | URB2 ribosome biogenesis homolog, nucleolar preribosomal-associated protein 2 |
| Synonyms | KIAA0133, LCO1, mKIAA0133, NET10, NPA2, RGD1307980, URB2 ribosome biogenesis 2 homolog (S. cerevisiae), URB2 ribosome biogenesis homolog |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human URB2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Urb2/Npa2 family
- leucine zipper domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- aggresome
- Cytoplasm
- cellular membrane
- midbody
- nucleoli
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human URB2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosome biogenesis
Cellular Component
Where in the cell the gene product is active
- midbody
- nucleolus
- aggresome