RTP4 Gene Summary [Human]
Predicted to enable olfactory receptor binding activity. Involved in defense response to virus; detection of chemical stimulus involved in sensory perception of bitter taste; and protein targeting to membrane. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RTP4 |
| Official Name | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] |
| Ensembl ID | ENSG00000136514 |
| Bio databases IDs | |
| Aliases | receptor transporter protein 4, zinc finger, 3CxxC-type 4 |
| Synonyms | 5830458K16Rik, IFRG28, receptor (chemosensory) transporter protein 4, receptor transporter protein 4, RGD1306974, Z3CXXC4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RTP4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc-binding domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- psoriasis
- Huntington disease
- insulin-dependent diabetes mellitus
- early onset hypertension
- plexiform neurofibroma
- hyperzincemia and hypercalprotectinemia autoinflammatory syndrome
- dermatomyositis
regulates
role in cell
- survival
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RTP4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- defense response to virus
- detection of chemical stimulus involved in sensory perception of bitter taste
- protein targeting to membrane
- protein insertion into membrane
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- olfactory receptor binding