C9orf78 Gene Summary [Human]
Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | C9orf78 |
| Official Name | chromosome 9 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:24932] |
| Ensembl ID | ENSG00000136819 |
| Bio databases IDs | |
| Aliases | chromosome 9 open reading frame 78, Hepatocellular carcinoma-associated antigen 59 |
| Synonyms | bA409K20.3, BC005624, C3h9orf78, cDNA sequence BC005624, chromosome 9 open reading frame 78, CSU2, HCA59, HSPC220, LOC51759, RGD1305178, similar to human chromosome 9 open reading frame 78, TLS1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human C9orf78 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- U5 snRNA binding
- Hepatocellular carcinoma-associated antigen 59
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
- centromeres
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human C9orf78 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA cis splicing, via spliceosome
- regulation of homologous chromosome segregation
- chromosome segregation
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- spliceosomal complex
- cytosol
- chromosome, centromeric region
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- U5 snRNA binding
- protein binding