RABEPK Gene Summary [Human]
Predicted to be involved in receptor-mediated endocytosis and vesicle docking involved in exocytosis. Predicted to be located in cytoplasmic vesicle; cytosol; and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RABEPK |
| Official Name | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] |
| Ensembl ID | ENSG00000136933 |
| Bio databases IDs | |
| Aliases | Rab9 effector protein with kelch motifs |
| Synonyms | 8430412M01RIK, 9530020D24Rik, AV073337, bA65N13.1, p40, Rab9 effector protein with kelch motifs, RAB9P40 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RABEPK often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Galactose oxidase, central domain
- Kelch motif
- protein binding
- Kelch domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- anxiety disorder
- substance-related disorder
- opioid-related disorder
- cannabis dependence
- infection by HIV-1
- productive infection by HIV-1
regulates
role in cell
- docking
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane fraction
- intracellular membrane-bounded organelle
- cellular membrane
- endosomes
- cytosol
- trans Golgi network
- transport vesicles
- cytosolic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RABEPK gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle docking involved in exocytosis
- receptor-mediated endocytosis
Cellular Component
Where in the cell the gene product is active
- endosome
- intracellular membrane-bounded organelle
- cytosol
- endosome membrane
- transport vesicle
- trans-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- protein binding