BUD13 Gene Summary [Human]
Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleoplasm. Part of U2-type precatalytic spliceosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | BUD13 |
| Official Name | BUD13 homolog [Source:HGNC Symbol;Acc:HGNC:28199] |
| Ensembl ID | ENSG00000137656 |
| Bio databases IDs | |
| Aliases | BUD13 homolog, functional spliceosome-associated protein 71 |
| Synonyms | BUD13 homolog, Cwc26, D030060M11Rik, fSAP71, RGD1308076 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human BUD13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Pre-mRNA-splicing factor of RES complex
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human BUD13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- RES complex
- spliceosomal complex
- U2-type spliceosomal complex
- U2-type precatalytic spliceosome
- U2 snRNP
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding