RSL24D1 Gene Summary [Human]

This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The protein encoded by this gene localizes to the nucleolus and is thought to play a role in the biogenesis of the 60S ribosomal subunit. The precise function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals and has multiple pseudogenes. [provided by RefSeq, Jul 2012]

Details

Type
Protein Coding
Official Symbol
RSL24D1
Official Name
ribosomal L24 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18479]
Ensembl ID
ENSG00000137876
Bio databases IDs NCBI: 51187 Ensembl: ENSG00000137876
Aliases ribosomal L24 domain containing 1
Synonyms 2410159K22Rik, C15orf15, HRP-L30-iso, L30, RGD1309784, ribosomal L24 domain containing 1, RLP24, RPL24, RPL24L, TVAS3
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RSL24D1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ribosomal protein L24e
  • protein binding
  • Putative metal-binding domain of cation transport ATPase
  • Ribosomal_L24e_L24

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-small cell lung cancer
  • metabolic syndrome X
  • coronary artery disease
  • nonalcoholic fatty liver disease
regulated by
  • RICTOR
  • Influenza A virus (A/Japan/305/57(H2N2))
  • PHF12
  • butylphen
role in cell
  • replication in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RSL24D1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal large subunit biogenesis
  • translation

Cellular Component

Where in the cell the gene product is active
  • ribosome
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.